Mary C. Theroux, MD

Anesthesiology

Primary Office

Nemours Children's Hospital, Delaware Nemours Children's Hospital, Delaware 1600 Rockland Road Wilmington, DE 19803 Appointment: (800) 416-4441

Other Offices

Get to Know Me

I have been practicing pediatric anesthesiology at Nemours/Alfred I. duPont Hospital for Children for 23 years. I was awarded the Best Anesthesiologist Award in 2006, and I also became a full professor of anesthesiology and pediatrics in 2010. In my personal life, my husband is a retired civil engineer, and I have a son who majored in physics and business in college, and is now starting down his own path in medicine.

Why I Treat Children

If there was a group of people who, above all others, always deserve the highest levels of care, wouldn't it be children? Returning joy to the innocent lives of children has been my motivation as a doctor for over twenty years, and it will continue to be for the rest of my career. Take it from me, there is no better place to make sadness and tears transform into happiness and laughter than a hospital for children.

What I'm Passionate About

As a physician, I believe that I have a responsibility to care for the whole person, not just the injury or illness. My goal every day is to return my patients not only to a state of health through medical science, but also to a state of happiness through compassion. This goal extends to the parents and families of my patients as well, since their emotions often suffer just as much as their children's, if not more so.

How I Try to Make A Difference

Although the primary objective of a physician should be to care for the patients of today, a career full of experience and training in medicine also yields the opportunity to make a difference for the patients of tomorrow through clinical research and mentoring. With this mindset, I have dedicated a large portion of my career to investigative work aimed at advancing the practice of anesthesiology. I also love the opportunity to bring undergraduate premedical students into the OR with me to give them their first glimpse of how amazing a career in medicine can be.

Education & Training

Fellowship

  • Pediatric Anesthesiology - University of Pittsburgh School of Medicine, 1989

Residency

  • Anesthesiology - University of South Florida, 1988
  • Pediatrics - City of Faith Hospital/Oral Roberts University, 1986

Medical/Dental School

  • MD - St. John's Medical College, 1981

Board Certifications

  • American Board of Anesthesiology/Pediatric Anesthesiology
  • American Board of Anesthesiology
  • American Board of Pediatrics/Pediatrics

Awards & Recognition

  • 2014 Delaware Today magazine, Top Doctors

Insurance Accepted

  • Aetna Better Health PA Kids HMO
  • Aetna HMO
  • Aetna PPO/EPO/POS
  • Aetna PPO/POS/EPO
  • Amerihealth Caritas DE - PENNSYLVANIA SPECIALISTS ONLY
  • Amerihealth Caritas Delaware
  • Amerihealth Caritas Delaware NJ
  • Cigna & Great West HMO/POS/EPO
  • Cigna & Great West PPO
  • Cigna Lifesource Transplant
  • Cigna/Great West HMO EPO POS
  • Cigna/Great West PPO
  • Delaware First Health
  • Delaware Medicaid/Diamond State
  • Delaware Medicare
  • Devon Health Services
  • Fidelis Care NJ Medicaid HMO
  • First Health/Affordable PPO
  • Geisinger Health Plan Commercial
  • Global Medical Managment DE/PA
  • Global Medical Mangment NJ
  • Health Partners Medicaid/Kidz Partner HMO
  • Highmark Blue Cross Blue Shield of Delaware
  • Highmark Blue Cross Blue Shield of Pennsylvania
  • Highmark Medicaid Health Options
  • Horizon Blue Cross Blue Shield of New Jersey
  • Independance Blue Cross/Amerihealth/Keystone Health Plan
  • Insurance Administrators of America
  • INTEGRA Administrative Group (ClaimsBridge)
  • Keystone First Medicaid HMO
  • Lifetrac Transplant
  • Maryland Medicaid
  • Multiplan PPO
  • New Jersey Medicaid
  • Pennsylvania Medicaid
  • Plan Vista/NPPN PPO
  • Preferred Healthcare PPO
  • Private Health Care Systems (PHCS)
  • Qualcare HMO/POS/PPO
  • Star Healthcare Network
  • Three Rivers Provider Network
  • Tricare/Humana Military Health Services
  • United Healthcare of the Mid-Atlantic
  • UPMC MCAID/CHIP PA DE
  • UPMC Medicaid
  • US Family Health Plan
  • Wellpoint Maryland Medcaid

  • Skeletal Dysplasia

Research Activities

As of 2013, I have published over 30 peer-reviewed papers on such topics as cerebral palsy, skeletal dysplasia, muscular dystrophy, and anesthesia for orthopedic surgery. I have also authored ten chapters in books used to teach new and emerging anesthesiologists.

Medical Interests

  • Cerebral palsy
  • One-lung ventilation
  • Skeletal dysplasia

  • Savarirayan, R., Ireland, P., Irving, M., Thompson, D., Alves, I., Baratela, W. A. R., & Fredwall, S. O. (2022). International Consensus Statement on the diagnosis, multidisciplinary management and lifelong care of individuals with achondroplasia. Nature Reviews Endocrinology, 18(3), 173-189. doi:10.1038/s41574-021-00595-x

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  • Theroux, M. C., & Campbell, J. W. (2022). Anesthetic Concerns of Children With Skeletal Dysplasia. Neurosurgery Clinics of North America, 33(1), 37-47. doi:10.1016/j.nec.2021.09.004

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  • Savarirayan, R., Ireland, P., Irving, M., Thompson, D., Alves, I., Baratela, W. A. R., & Fredwall, S. O. (2022). International Consensus Statement on the diagnosis, multidisciplinary management and lifelong care of individuals with achondroplasia. Nature Reviews Endocrinology, 18(3), 173-189. doi:10.1038/s41574-021-00595-x

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  • Savarirayan, R., Ireland, P., Irving, M., Thompson, D., Alves, I., Baratela, W. A. R., & Fredwall, S. O. (2022). International Consensus Statement on the diagnosis, multidisciplinary management and lifelong care of individuals with achondroplasia. Nature Reviews Endocrinology, 18(3), 173-189. doi:10.1038/s41574-021-00595-x

  • Lee, S., Robinson, K., Lodge, M., Theroux, M., Miller, F., & Akins, R., Jr. (2021). Resistance to neuromuscular blockade by rocuronium in surgical patients with spastic cerebral palsy. Journal of Personalized Medicine, 11(8). doi:10.3390/jpm11080765

  • Averill, L. W., Kecskemethy, H. H., Theroux, M. C., Mackenzie, W. G., Pizarro, C., Bober, M. B., & Tomatsu, S. (2021). Tracheal narrowing in children and adults with mucopolysaccharidosis type IVA: evaluation with computed tomography angiography. Pediatric Radiology, 51(7), 1202-1213. doi:10.1007/s00247-020-04946-0

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  • Savarirayan, R., Ireland, P., Irving, M., Thompson, D., Alves, I., Baratela, W. A. R., & Fredwall, S. O. (2022). International Consensus Statement on the diagnosis, multidisciplinary management and lifelong care of individuals with achondroplasia. Nature Reviews Endocrinology, 18(3), 173-189. doi:10.1038/s41574-021-00595-x

  • Ratnagiri, M. V., Zhu, Y., Rahman, T., Theroux, M., Tomatsu, S., & Shaffer, T. H. (2021). Automated assessment of thoracic-abdominal asynchrony in patients with morquio syndrome. Diagnostics, 11(5). doi:10.3390/diagnostics11050880

  • Stapleton, M., Hoshina, H., Sawamoto, K., Kubaski, F., Mason, R. W., Mackenzie, W. G., & Tomatsu, S. (2019). Critical review of current MPS guidelines and management. Molecular Genetics and Metabolism, 126(3), 238-245. doi:10.1016/j.ymgme.2018.07.001

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  • Litman, R. S., Smith, V. I., Larach, M. G., Mayes, L., Shukry, M., Theroux, M. C., & Wong, C. A. (2019). Consensus Statement of the Malignant Hyperthermia Association of the United States on Unresolved Clinical Questions Concerning the Management of Patients With Malignant Hyperthermia. Anesthesia and analgesia, 128(4), 652-659. doi:10.1213/ANE.0000000000004039

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  • Peracha, H., Sawamoto, K., Averill, L., Kecskemethy, H., Theroux, M., Thacker, M., & Tomatsu, S. (2018). Molecular genetics and metabolism, special edition: Diagnosis, diagnosis and prognosis of Mucopolysaccharidosis IVA. Molecular Genetics and Metabolism, 125(1-2), 18-37. doi:10.1016/j.ymgme.2018.05.004

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  • Doherty, C., Averill, L. W., Theroux, M., Mackenzie, W. G., Pizarro, C., Mason, R. W., & Tomatsu, S. (2018). Natural history of Morquio A patient with tracheal obstruction from birth to death. Molecular Genetics and Metabolism Reports, 14, 59-67. doi:10.1016/j.ymgmr.2017.11.005

  • Brenn, B. R., Theroux, M. T., Shah, S. A., Mackenzie, W. G., Heinle, R., & Scavina, M. T. (2018). Critical airway stenosis in an adolescent male with pompe disease and thoracic lordosis: A case report. In 100 Selected Case Reports from Anesthesia and Analgesia. doi:10.1213/XAA.0000000000000564

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  • Dixit, D., Theroux, M. C., Dabney, K. W., & Miller, F. (2018). Use of caudal epidural catheter in a child with cerebral palsy with prior posterior spine (T1-sacrum) fusion. Indian Journal of Anaesthesia, 62(1), 80-82. doi:10.4103/ija.IJA_562_17

  • White, K. K., Bompadre, V., Goldberg, M. J., Bober, M. B., Cho, T.-J., Hoover-Fong, J. E., & On behalf of the Skeletal Dysplasia Management Consortium. (2017). Best practices in peri-operative management of patients with skeletal dysplasias. American Journal of Medical Genetics, Part A, 173(10), 2584-2595. doi:10.1002/ajmg.a.38357

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  • Theroux, M. C., Lopez, M., Olszewsky, P. J., DiCindio, S., Arai, L., Ditro, C., & Mackenzie, W. G. (2017). Metatropic dysplasia: a skeletal dysplasia with challenging airway and other anesthetic concerns. Paediatric Anaesthesia, 27(6), 596-603. doi:10.1111/pan.13101

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  • Khan, S., Almeciga-Diaz, C. J., Sawamoto, K., Mackenzie, W. G., Theroux, M. C., Pizarro, C., & Tomatsu, S. (2017). Mucopolysaccharidosis IVA and glycosaminoglycans. Molecular Genetics and Metabolism, 120(1-2), 78-95. doi:10.1016/j.ymgme.2016.11.007

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  • Tomatsu, S., Averill, L. W., Sawamoto, K., Mackenzie, W. G., Bober, M. B., Pizarro, C., & Theroux, M. (2016). Obstructive airway in Morquio A syndrome, the past, the present and the future. Molecular Genetics and Metabolism, 117(2), 150-156. doi:10.1016/j.ymgme.2015.09.007

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  • Eiszner, J. R., Atanda, A., Jr, Rangavajjula, A., & Theroux, M. (2016). A case series of peripheral nerve blocks in pediatrics and young adults with skeletal dysplasia. Paediatric Anaesthesia, 26(5), 553-556. doi:10.1111/pan.12875

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  • Yasuda, E., Suzuki, Y., Shimada, T., Sawamoto, K., Mackenzie, W. G., Theroux, M. C., & Tomatsu, S. (2016). Activity of daily living for Morquio A syndrome. Molecular Genetics and Metabolism, 118(2), 111-122. doi:10.1016/j.ymgme.2016.04.005

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  • Sawamoto, K., Suzuki, Y., Mackenzie, W. G., Theroux, M. C., Pizarro, C., Yabe, H., & Tomatsu, S. (2016). Current therapies for Morquio A syndrome and their clinical outcomes. Expert Opinion on Orphan Drugs, 4(9), 941-951. doi:10.1080/21678707.2016.1214572

  • Pizarro, C., Davies, R. R., Theroux, M., Spurrier, E. A., Averill, L. W., & Tomatsu, S. (2016). Surgical Reconstruction for Severe Tracheal Obstruction in Morquio A Syndrome. Annals of Thoracic Surgery, 102(4), e329-e331. doi:10.1016/j.athoracsur.2016.02.113

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  • Charrow, J., Alden, T. D., Breathnach, C. A. R., Frawley, G. P., Hendriksz, C. J., Link, B., & Theroux, M. (2015). Diagnostic evaluation, monitoring, and perioperative management of spinal cord compression in patients with Morquio syndrome. Molecular Genetics and Metabolism, 114(1), 11-18. doi:10.1016/j.ymgme.2014.10.010

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  • Drummond, J. C., Krane, E. J., Tomatsu, S., Theroux, M. C., & Lee, R. R. (2015). Paraplegia after epidural-general anesthesia in a Morquio patient with moderate thoracic spinal stenosis. Canadian Journal of Anesthesia, 62(1), 45-49. doi:10.1007/s12630-014-0247-1

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  • Theroux, M. C., Fisher, A. O., Rodriguez, M. E., Brislin, R. P., Reichard, K. W., Shah, S. A., & Shaffer, T. H. (2015). Prophylactic methylprednisolone to reduce inflammation and improve outcomes from one lung ventilation in children: A randomized clinical trial. Paediatric Anaesthesia, 25(6), 587-594. doi:10.1111/pan.12601

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  • DiCindio, S., Arai, L., McCulloch, M., Sadacharam, K., Shah, S. A., Gabos, P., & Theroux, M. C. (2015). Clinical relevance of echocardiogram in patients with cerebral palsy undergoing posterior spinal fusion. Paediatric Anaesthesia, 25(8), 840-845. doi:10.1111/pan.12676

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  • Kubaski, F., Tomatsu, S., Patel, P., Shimada, T., Xie, L., Yasuda, E., & Shaffer, T. H. (2015). Non-invasive pulmonary function test on Morquio patients. Molecular Genetics and Metabolism, 115(4), 186-192. doi:10.1016/j.ymgme.2015.06.007

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  • Theroux, M. C., Olivant Fisher, A., Rodriguez, M., Brislin, R. P., Reichard, K. W., Shah, S. A., & Brown, M. (2015). Response to comments by Yibo et al. regarding our manuscript: Prophylactic methylprednisolone to reduce inflammation and improve outcomes from one lung ventilation in children: A randomized clinical trial. Paediatric Anaesthesia, 25(10), 1066-1067. doi:10.1111/pan.12725

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